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Salgia, Ravi
One or more keywords matched the following items that are connected to Salgia, Ravi
Item TypeName
Concept Drug Evaluation, Preclinical
Concept Feasibility Studies
Concept Mice, Inbred Strains
Concept Models, Molecular
Concept Mice, Transgenic
Concept Models, Genetic
Concept Models, Theoretical
Concept Mice, Inbred BALB C
Concept Mice, Inbred C57BL
Concept Mice, Nude
Concept Cohort Studies
Concept Linear Models
Concept Multicenter Studies as Topic
Concept Proportional Hazards Models
Concept Case-Control Studies
Concept Mice, Knockout
Concept Mice
Concept National Cancer Institute (U.S.)
Concept Logistic Models
Concept Disease Models, Animal
Concept Follow-Up Studies
Concept Models, Biological
Concept Prospective Studies
Concept Retrospective Studies
Concept Mice, SCID
Concept Mice, Inbred NOD
Concept Mice, Inbred SENCAR
Academic Article Interleukin-3 and p210 BCR/ABL activate both unique and overlapping pathways of signal transduction in a factor-dependent myeloid cell line.
Academic Article Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL.
Academic Article p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene.
Academic Article BCR/ABL induces multiple abnormalities of cytoskeletal function.
Academic Article The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells.
Academic Article The phosphatidylinositol polyphosphate 5-phosphatase SHIP and the protein tyrosine phosphatase SHP-2 form a complex in hematopoietic cells which can be regulated by BCR/ABL and growth factors.
Academic Article The BCR/ABL oncogene alters interaction of the adapter proteins CRKL and CRK with cellular proteins.
Academic Article Hematopoietic growth factors signal through the formation of reactive oxygen species.
Academic Article Thrombopoietin induces activation of the phosphatidylinositol-3' kinase pathway and formation of a complex containing p85PI3K and the protooncoprotein p120CBL.
Academic Article Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571.
Academic Article The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells.
Academic Article The BCR/ABL oncogene alters the chemotactic response to stromal-derived factor-1alpha.
Academic Article Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells.
Academic Article Expression of the focal adhesion protein paxillin in lung cancer and its relation to cell motility.
Academic Article Gemcitabine and vinorelbine in patients with advanced lung cancer: preclinical studies and report of a phase I trial.
Academic Article ATP6S1 elicits potent humoral responses associated with immune-mediated tumor destruction.
Academic Article Differential expression and signaling of CBL and CBL-B in BCR/ABL transformed cells.
Academic Article SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL.
Academic Article Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition.
Academic Article Cell motility, adhesion, homing, and migration assays in the studies of tyrosine kinases.
Academic Article Gemcitabine-induced radiation recall.
Academic Article Flow cytometric determination of lipid peroxidation using fluoresceinated phosphoethanolamine.
Academic Article c-MET mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions.
Academic Article 2-methoxyestradiol alters cell motility, migration, and adhesion.
Academic Article Molecular alterations in lung cancer. Impact on prognosis.
Academic Article Reliable and sensitive identification of occult tumor cells using the improved rare event imaging system.
Academic Article A selective small molecule c-MET Inhibitor, PHA665752, cooperates with rapamycin.
Academic Article c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention.
Academic Article A selective small molecule inhibitor of c-Met, PHA665752, inhibits tumorigenicity and angiogenesis in mouse lung cancer xenografts.
Academic Article Epidermal growth factor receptor - mediated signal transduction in the development and therapy of gliomas.
Academic Article The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma.
Academic Article Lymphatic vessel density is not associated with lymph node metastasis in non-small cell lung carcinoma.
Academic Article Role of c-Met in cancer: emphasis on lung cancer.
Academic Article PAX6 is expressed in pancreatic cancer and actively participates in cancer progression through activation of the MET tyrosine kinase receptor gene.
Academic Article Ethnic differences and functional analysis of MET mutations in lung cancer.
Academic Article c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion.
Academic Article The clinical presentation and prognostic factors for intrahepatic and extrahepatic cholangiocarcinoma in a tertiary care centre.
Academic Article The novel role of the mu opioid receptor in lung cancer progression: a laboratory investigation.
Academic Article Chemotherapy and high dose radiotherapy followed by resection for locally advanced nonsmall cell lung cancers.
Academic Article Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin.
Academic Article Preclinical studies of the proteasome inhibitor bortezomib in malignant pleural mesothelioma.
Academic Article Fyn is downstream of the HGF/MET signaling axis and affects cellular shape and tropism in PC3 cells.
Academic Article FYN is overexpressed in human prostate cancer.
Academic Article Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer.
Academic Article Autotaxin induces lung epithelial cell migration through lysoPLD activity-dependent and -independent pathways.
Academic Article Prognostic value of metabolic tumor burden on 18F-FDG PET in nonsurgical patients with non-small cell lung cancer.
Academic Article Overexpression of the µ-opioid receptor in human non-small cell lung cancer promotes Akt and mTOR activation, tumor growth, and metastasis.
Academic Article Erlotinib plus bevacizumab in previously treated patients with malignant pleural mesothelioma.
Academic Article Bortezomib for patients with advanced-stage bronchioloalveolar carcinoma: a California Cancer Consortium Phase II study (NCI 7003).
Academic Article Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL.
Academic Article Melanoma proteoglycan modifies gene expression to stimulate tumor cell motility, growth, and epithelial-to-mesenchymal transition.
Academic Article MET, HGF, EGFR, and PXN gene copy number in lung cancer using DNA extracts from FFPE archival samples and prognostic significance.
Academic Article Multicenter phase II trial of Motexafin gadolinium and pemetrexed for second-line treatment in patients with non-small cell lung cancer.
Academic Article MET and phosphorylated MET as potential biomarkers in lung cancer.
Academic Article Functional EGFR germline polymorphisms may confer risk for EGFR somatic mutations in non-small cell lung cancer, with a predominant effect on exon 19 microdeletions.
Academic Article Role of protein kinase C ß and vascular endothelial growth factor receptor in malignant pleural mesothelioma: Therapeutic implications and the usefulness of Caenorhabditis elegans model organism.
Academic Article Phase 2 trial of Linifanib (ABT-869) in patients with advanced non-small cell lung cancer.
Academic Article Control of bleeding in patients with immune and nonimmune thrombocytopenia with aminocaproic acid.
Academic Article MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib.
Academic Article Hypofractionated image-guided radiation therapy for patients with limited volume metastatic non-small cell lung cancer.
Academic Article Sphingosine kinase 1 is required for mesothelioma cell proliferation: role of histone acetylation.
Academic Article Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion.
Academic Article Novel oncogenic mutations of CBL in human acute myeloid leukemia that activate growth and survival pathways depend on increased metabolism.
Academic Article NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases.
Academic Article An E3 ubiquitin ligase: c-Cbl: a new therapeutic target of lung cancer.
Academic Article Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer.
Academic Article Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis.
Academic Article The American Association for Thoracic Surgery guidelines for lung cancer screening using low-dose computed tomography scans for lung cancer survivors and other high-risk groups.
Academic Article Phase II study of the multitargeted tyrosine kinase inhibitor XL647 in patients with non-small-cell lung cancer.
Academic Article Targeting ALK: a promising strategy for the treatment of non-small cell lung cancer, non-Hodgkin's lymphoma, and neuroblastoma.
Academic Article Three-dimensional stereoscopic volume rendering of malignant pleural mesothelioma.
Academic Article Involvement of the adapter protein CRKL in integrin-mediated adhesion.
Academic Article Detection and analysis of lung cancer cells from body fluids using a rare event imaging system.
Academic Article A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase.
Academic Article A phase I study of pemetrexed, carboplatin, and concurrent radiotherapy in patients with locally advanced or metastatic non-small cell lung or esophageal cancer.
Academic Article CD44 regulates hepatocyte growth factor-mediated vascular integrity. Role of c-Met, Tiam1/Rac1, dynamin 2, and cortactin.
Academic Article Quality of life after radical pleurectomy decortication for malignant pleural mesothelioma.
Academic Article Degradation and regurgitation of extracellular proteins by cultured mouse peritoneal macrophages and baby hamster kidney fibroblasts. Kinetic evidence that the transfer of proteins to lysosomes is not irreversible.
Academic Article Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR/ABL.
Academic Article Critical role for the receptor tyrosine kinase EPHB4 in esophageal cancers.
Academic Article Lack of association of C-Met-N375S sequence variant with lung cancer susceptibility and prognosis.
Academic Article The EphB4 receptor tyrosine kinase promotes lung cancer growth: a potential novel therapeutic target.
Academic Article Nuclear EGFR protein expression predicts poor survival in early stage non-small cell lung cancer.
Academic Article Critical role of S1PR1 and integrin ß4 in HGF/c-Met-mediated increases in vascular integrity.
Academic Article EphB4 as a therapeutic target in mesothelioma.
Academic Article Transactivation of the receptor-tyrosine kinase ephrin receptor A2 is required for the low molecular weight hyaluronan-mediated angiogenesis that is implicated in tumor progression.
Academic Article Role of c-Met/phosphatidylinositol 3-kinase (PI3k)/Akt signaling in hepatocyte growth factor (HGF)-mediated lamellipodia formation, reactive oxygen species (ROS) generation, and motility of lung endothelial cells.
Academic Article Activating the expression of human K-rasG12D stimulates oncogenic transformation in transgenic goat fetal fibroblast cells.
Academic Article MET and PI3K/mTOR as a potential combinatorial therapeutic target in malignant pleural mesothelioma.
Academic Article Leptomeningeal carcinomatosis in esophageal cancer: a case series and systematic review of the literature.
Academic Article Non-small cell lung cancer is susceptible to induction of DNA damage responses and inhibition of angiogenesis by telomere overhang oligonucleotides.
Academic Article Dramatic antitumor effects of the dual MET/RON small-molecule inhibitor LY2801653 in non-small cell lung cancer.
Academic Article Geographic variation in radiologist capacity and widespread implementation of lung cancer CT screening.
Academic Article AXL mediates resistance to cetuximab therapy.
Academic Article Overcoming acquired resistance to cetuximab by dual targeting HER family receptors with antibody-based therapy.
Academic Article Nuclear epidermal growth factor receptor is a functional molecular target in triple-negative breast cancer.
Academic Article c-Abl mediated tyrosine phosphorylation of paxillin regulates LPS-induced endothelial dysfunction and lung injury.
Academic Article AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma.
Academic Article Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung Cancer.
Academic Article A randomized phase II study of ganetespib, a heat shock protein 90 inhibitor, in combination with docetaxel in second-line therapy of advanced non-small cell lung cancer (GALAXY-1).
Academic Article Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
Academic Article PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma.
Academic Article Whole-animal mounts of Caenorhabditis elegans for 3D imaging using atomic force microscopy.
Academic Article Lung cancer-a fractal viewpoint.
Academic Article Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer.
Academic Article FAK and paxillin, two potential targets in pancreatic cancer.
Academic Article Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.
Academic Article Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab.
Academic Article PI3 Kinase Pathway and MET Inhibition is Efficacious in Malignant Pleural Mesothelioma.
Academic Article RETRACTED: The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor.
Academic Article Molecular profiling of metastatic colorectal tumors using next-generation sequencing: a single-institution experience.
Academic Article A randomized phase II study of LY2510924 and carboplatin/etoposide versus carboplatin/etoposide in extensive-disease small cell lung cancer.
Academic Article Capecitabine and Celecoxib as a Promising Therapy for Thymic Neoplasms.
Academic Article Differential responsiveness of MET inhibition in non-small-cell lung cancer with altered CBL.
Academic Article Current and Future Management of Malignant Mesothelioma: A Consensus Report from the National Cancer Institute Thoracic Malignancy Steering Committee, International Association for the Study of Lung Cancer, and Mesothelioma Applied Research Foundation.
Academic Article Phase 1 Study of Accelerated Hypofractionated Radiation Therapy With Concurrent Chemotherapy for Stage III Non-Small Cell Lung Cancer: CALGB 31102 (Alliance).
Academic Article Modeling small cell lung cancer (SCLC) biology through deterministic and stochastic mathematical models.
Academic Article 2'-Hydroxyflavanone inhibits in vitro and in vivo growth of breast cancer cells by targeting RLIP76.
Academic Article Metastasis of breast tumor cells to brain is suppressed by targeting RLIP alone and in combination with 2'-Hydroxyflavanone.
Academic Article Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma.
Academic Article B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies.
Academic Article RLIP inhibition suppresses breast-to-lung metastasis.
Academic Article Anaplastic Lymphoma Kinase (ALK)-positive Tumors: Clinical, Radiographic and Molecular Profiles, and Uncommon Sites of Metastases in Patients With Lung Adenocarcinoma.
Academic Article The gut microbiome and response to immune checkpoint inhibitors: preclinical and clinical strategies.
Academic Article Synergistic efficacy of RLIP inhibition and 2'-hydroxyflavanone against DMBA-induced mammary carcinogenesis in SENCAR mice.
Academic Article Optimal adjuvant therapy in clinically N2 non-small cell lung cancer patients undergoing neoadjuvant chemotherapy and surgery: The importance of pathological response and lymph node ratio.
Academic Article Radiologic Considerations and Standardization of Malignant Pleural Mesothelioma Imaging Within Clinical Trials: Consensus Statement from the NCI Thoracic Malignancy Steering Committee - International Association for the Study of Lung Cancer - Mesothelioma Applied Research Foundation Clinical Trials Planning Meeting.
Academic Article USP22 Interacts with PALB2 and Promotes Chemotherapy Resistance via Homologous Recombination of DNA Double-Strand Breaks.
Academic Article Dose-escalation trial of the ALK, MET & ROS1 inhibitor, crizotinib, in patients with advanced cancer.
Academic Article Ubiquitin-specific protease 22 is critical to in vivo angiogenesis, growth and metastasis of non-small cell lung cancer.
Academic Article Presence and structure-activity relationship of intrinsically disordered regions across mucins.
Academic Article Precision medicine and actionable alterations in lung cancer: A single institution experience.
Academic Article Association of TGF-ß1 Polymorphisms with Breast Cancer Risk: A Meta-Analysis of Case-Control Studies †.
Academic Article Radiomic prediction of mutation status based on MR imaging of lung cancer brain metastases.
Academic Article Phase I Dose-Escalation and -Expansion Study of Telisotuzumab (ABT-700), an Anti-c-Met Antibody, in Patients with Advanced Solid Tumors.
Academic Article Differentiating Peripherally-Located Small Cell Lung Cancer From Non-small Cell Lung Cancer Using a CT Radiomic Approach.
Academic Article AXL Mediates Cetuximab and Radiation Resistance Through Tyrosine 821 and the c-ABL Kinase Pathway in Head and Neck Cancer.
Academic Article Opportunities for improving cancer treatment using systems biology.
Academic Article Association of molecular characteristics with survival in advanced non-small cell lung cancer patients treated with checkpoint inhibitors.
Academic Article Evaluation of Omics-Based Strategies for the Management of Advanced Lung Cancer.
Academic Article Lysocardiolipin acyltransferase regulates NSCLC cell proliferation and migration by modulating mitochondrial dynamics.
Academic Article The Effects of Time to Treatment Initiation for Patients With Non-small-cell Lung Cancer in the United States.
Academic Article Inhibitors of the Transcription Factor STAT3 Decrease Growth and Induce Immune Response Genes in Models of Malignant Pleural Mesothelioma (MPM).
Academic Article Prevention of mammary carcinogenesis in MMTV-neu mice by targeting RLIP.
Academic Article Durvalumab for Stage III EGFR-Mutated NSCLC After Definitive Chemoradiotherapy.
Academic Article RLIP depletion induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells.
Academic Article Quantifying Cancer: More Than Just a Numbers Game.
Academic Article Improved Survival Outcomes in Medically Fit Patients With Early-Stage Non-Small-Cell Lung Cancer Undergoing Stereotactic Body Radiotherapy.
Academic Article Disparate outcomes in nonsmall cell lung cancer by immigration status.
Academic Article RNA-based therapies: A cog in the wheel of lung cancer defense.
Academic Article Multicohort Retrospective Validation of a Predictive Biomarker for Topoisomerase I Inhibitors.
Academic Article ST6GalNAc-I promotes lung cancer metastasis by altering MUC5AC sialylation.
Academic Article Germline mutations and age at onset of lung adenocarcinoma.
Academic Article Usefulness of Circulating Tumor DNA in Identifying Somatic Mutations and Tracking Tumor Evolution in Patients With Non-small Cell Lung Cancer.
Academic Article The Association between Polluted Neighborhoods and TP53-Mutated Non-Small Cell Lung Cancer.
Academic Article Essential role of the histone lysine demethylase KDM4A in the biology of malignant pleural mesothelioma (MPM).
Academic Article JNJ-64041757 (JNJ-757), a Live, Attenuated, Double-Deleted Listeria monocytogenes-Based Immunotherapy in Patients With NSCLC: Results From Two Phase 1 Studies.
Academic Article Infectious complications of immune checkpoint inhibitors in solid organ malignancies.
Academic Article Patterns of Care in Maintenance Therapy in US Patients Undergoing Definitive Chemoradiation for Stage 3 Non-Small Cell Lung Cancer (NSCLC).
Academic Article Dynamic Phenotypic Switching and Group Behavior Help Non-Small Cell Lung Cancer Cells Evade Chemotherapy.
Academic Article Postoperative Radiation Therapy Should Be Used for Completely Resected Stage III-N2 NSCLC in Select Patients.
Academic Article Machine learning to refine prognostic and predictive nodal burden thresholds for post-operative radiotherapy in completely resected stage III-N2 non-small cell lung cancer.
Academic Article MicroRNA-1 attenuates the growth and metastasis of small cell lung cancer through CXCR4/FOXM1/RRM2 axis.
Academic Article RLIP: A necessary transporter protein for translating oxidative stress into pro-obesity and pro-carcinogenic signaling.
Academic Article Prognostic Role of Biologically Active Volume of Disease in Patients With Metastatic Lung Adenocarcinoma.
Concept Clinical Studies as Topic
Grant ABNORMALITIES OF MOTILITY OF CML CELLS
Grant Role of Paxillin in Lung Cancer
Grant Role of c-Met in SCLC and Potential for Novel Therapy
Grant Novel Targeted Therapy in Pancreatic Cancer
Grant Studies of a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC)
Grant PAXILLIN--AN ONCOGENE ACTIVATED PROTEIN
Academic Article Twelve-Month Follow-up of the Immune Response After COVID-19 Vaccination in Patients with Genitourinary Cancers: A Prospective Cohort Analysis.
Academic Article Dual Axl/MerTK inhibitor INCB081776 creates a proinflammatory tumor immune microenvironment and enhances anti-PDL1 efficacy in head and neck cancer.
Academic Article Recent Advancement in Breast Cancer Research: Insights from Model Organisms-Mouse Models to Zebrafish.
Academic Article Radiation Sensitivity: The Rise of Predictive Patient-Derived Cancer Models.
Academic Article Stereotactic Body Radiation Therapy for Oligoprogressive and Oligorecurrent Non-Small-Cell Lung Cancer.
Academic Article Targeting ITGB4/SOX2-driven lung cancer stem cells using proteasome inhibitors.
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  • mouse
  • models